Antibody development works much like any engineering feat; you get out what you put in. With the shotgun approach to developing polyclonal antibodies, hitting the target usually isn’t too much of a problem, but the immune response can be nonspecific.
Antibody Basics: Isotypes
Antibodies come in several shapes and sizes, leading to a variance in properties and purposes. Below is a broad outline of each of the major isotypes of antibodies and how they are used. Some isotypes can be isolated incredibly easily
The Antibody Basics Series: Table of Contents
Not too long ago, we published The 5 A’s of Antibodies infographic, which provides a brief explanation of all what goes into the process of generating custom antibodies against specific targets. Our next step is to begin providing summaries of
Antibody Basics: Hybridoma
Hybridoma Development Hybridoma technology is the core technique used to develop monoclonal antibodies at ProSci. A hybridoma is a single cell that consists of a cancerous myeloma cell and an immune B-cell which have been fused together into a single