The MHC Monomer is a sub-component of an MHC Tetramer. Biotinylated Monomers are available for most associated Tetramer products.
Why is the MHC monomer the ideal choice for your experimental design?
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The MHC Monomer is a sub-component of an MHC Tetramer. Biotinylated Monomers are available for most associated Tetramer products.
Adding another marker to a flow cytometry panel can present a challenge when trying to accommodate all markers of interest in one panel. However, there is a solution.
MBL International provides QuickSwitch™ Tetramers for the Quant Analysis of SARS-CoV-2 mRNA Vaccinations.
MBLI QuickSwitch™ kit technology aims to replicate the immune response by mimicking peptide exchange on an MHC molecule.
Use QuickSwitch™ Class II Quant Tetramer to investigate peptide-MHC binding affinities & conclude with your specialised CD4+ T cell detection reagent!
CD1d, non-classical MHC molecules, present phospholipid & glycosphingolipid antigens to iNKT cells. MBL tetramers help measure CD1d positive NKT cells
Here are the highlights of some of the influential publications that have utilised MBLI QuickSwitch™ Tetramer Kits in 2023.
A TCR Tetramer is a reagent prepared by tetramerising biotinylated antigen-specific TCRs with the help of phycobiliprotein-labelled streptavidin.
Wang, Wenfeng, et al 2023, selected the top 15 top peptides for self-antigen for their study. By using the QuickSwitch™ kit, they successfully switched 6 peptides to the tetramer complex with an efficiency of over 75%.
Negative controls aid precision of immune response monitoring. For HLA-A*02:01 alleles, MBLI offers a “Negative Tetramer” in BV421, PE or APC.