OLFR734 Mediates Glucose Metabolism as a Receptor of Asprosin

Asprosin is a fasting-induced hormone that increases plasma glucose levels in the liver. It also stimulates appetite in the hypothalamus by activating the cAMP signaling pathway via an unknown G protein-coupled receptor (GPCR). In a recent study, the lab of Yiguo Wang (Tsinghua University, 100084 Beijing, China) identifies the multipass G protein-coupled receptor olfactory receptor OLFR734, as the Asprosin receptor in liver. The Asprosin-OLFR734 axis plays a key role in hepatic glucose homeostasis during fasting and in obesity.

AdipoGen Life Sciences provides a recombinant protein, monoclonal antibodies and a detection set to study Asprosin.

– Asprosin (human) (rec.) (His) (Prod. No. AG-40B-0174T)

– anti-Asprosin, mAb (Birdy-1) (Prod. No. AG-20B-0073)

– anti-Asprosin (human), mAb (Birdy-2) (Prod. No. AG-20B-0074)

– Asprosin (human) Matched Pair Detection Set (Prod. No. AG-46B-0011)

LIT: OLFR734 Mediates Glucose Metabolism as a Receptor of Asprosin: E. Li, et al.; Cell Metabolism 30, 1 (2019)

OLFR734 Mediates Glucose Metabolism as a Receptor of Asprosin
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