As discussed in two prior blog posts, PCSK9 has primarily been studied for its role in regulating cholesterol levels and as a target for treatments to lower cholesterol. However, PCSK9 has been found to be involved in many other important pathways. This
Elevate your Cholesterol Research Part 2: How Our PCSK9 ELISA Kit Can Help You
As discussed in a previous blog post, inhibiting PCSK9 from binding to the LDL receptor results in lower LDL cholesterol levels in the bloodstream. Research on PCSK9 has explored how it can be targeted in treatments for hypercholesterolemia (high cholesterol)
Elevate Your Cholesterol Research: How a PCSK9 ELISA Kit Can Help You
Ever wonder how cholesterol levels are regulated? One of the major regulators is a molecule called proprotein convertase subtilisin/kexin type 9 or PCSK9 for short! PCSK9 has been implicated in causing hypercholesterolemia (high cholesterol), and diseases such as coronary heart
Stop Crying in the Lab: How Cry Antibodies Can Help Your Research
Tiredness and frustration often mount after long nights in the lab. Why can’t our bodies adjust and allow us to maintain our energy through the night? The answer lies in our circadian rhythms. Circadian rhythms are the daily cycle
Help! My mouse tetramer stained ALL the CD8+ T cells!
You’re sitting at your flow cytometer, staring at your CD8 x tetramer plot in anticipation of a tiny but meaningful group of dots appearing in the upper right quadrant. You hold your breath, click “acquire,” and watch… Wait, what? What’s
Colorimetric? Fluorometric? How to choose the right platform for your ELISA
What happens when you use a black well plate for a fluorometric ELISA assay reading? What happens when you use a clear well plate for a colorimetric ELISA assay reading? Well the short answer is that you made the right
Don’t FRET- You’ve got Fluoppi!
Visualizing protein-protein interaction (PPI) is pretty neat. You are able to glimpse into a really unique aspect of nature that many people don’t get to see. It’s like watching lions and zebras interact but without the bloody violence. However, anyone
Improve your RNA research using our anti-BrdU antibody!
How do you quantify newly synthesised RNA? There are several ways to detect synthesised RNA, but these methods have their complications. The 5-Bromouridine immunoprecipitation chase (BRIC) Kit offers the the most suitable method for RNA decay analysis. Regulation of gene expression by RNA degradation
Immunostaining of Circulating Tumour Cells in TransFix Stabilised Blood Samples
The presence of circulating tumour cells (CTC’s) has been shown to be of diagnostic relevance for patients with early and advanced breast cancer (BC). The usefulness of CTC assessments depends upon accurate cell counts and the corresponding analysis of molecular
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