A Guide to CD28, CTLA-4, and CD80/CD86 Interaction and Signaling Immune checkpoint receptors like CD28 and CTLA-4 have been of great interest in the research of cancer immunotherapy. These receptors and their ligands are part of what regulates T-cell activation
December 2016: The Antibody Update
Merck’s Ebola Vaccine is 100% Effective An extremely effective Ebola virus vaccine created by Merck was recently tested in Guinea with 100% effectiveness. Though the vaccine is late for the worst part of the infection, the results are so promising
November 2016: The Antibody Update
China Perform First Injection of CRISPR Modified Cells into a Person Use of CRISPR-Cas9 in human cells for treatment of disease has been a controversial topic amongst scientists since the discovery of the powerful gene editing tool. In this clinical
October 2016: The Antibody Update
The Nobel Prize in Medicine was Awarded to Yoshinori Ohsumi for His Work on Autophagy Autophagy is the cellular process that regulates a cells ability to degrade parts of itself that must be replaced. Yoshinori Ohsumi’s work in autophagy has proven to
August 2016: The Antibody Update from ProSci
ProSci’s top news picks for August 2016 include a study on T-cell activity inside tumor tissue, the potential effects of Zika virus in adults, and mRNA therapeutics. T-cells Run
June 2016: The Antibody Update from ProSci
This months ProSci Antibody Update’s news includes the first CRISPR/Cas9 cancer therapeutic’s entry into clinical trials, how mosquito saliva assists viruses in proliferation, and the latest update on antibody validation. First CRISPR/Cas9 Therapeutic Clinical Trials StartingProSci Blog Antibody UpdateCRISPR Cas9
What do mitochondria have to do with mitophagy?
What is mitophagy? It is when damaged mitochondria are removed from the cell by autophagy. The damaged mitochondria end up in lysosomes for their final disposal. This whole process is to maintain and assure proper cellular function. The importance of
“Let’s Make America the Country That Cures Cancer Once and For All”
During the 2016 State of the Union Address, President Obama called attention to a myriad of issues currently plaguing Americans. One of the many initiatives President Obama announced in response was a “moonshot” to cure cancer, referencing the flood of
February 2016: The Antibody Update
Check out ProSci’s February Antibody Update for the latest news in the industry – This month discusses the cancer moonshot project, an update on the Zika virus, and gravitational waves. The Cancer Moonshot Patrick Soon-Shiong, a billionaire entrepreneur of
A Brief Introduction to PD-1 Antibodies and Immunotherapy
President Jimmy Carter’s cancer remission was wonderful news, but as some outlets [1] noted, it is important to understand that not all patients are responding as well to similar treatments, and that there is currently still no “cure” for cancer.