An inflammasome represents a high molecular weight complex that activates inflammatory caspases and activates cytokines of the IL-1 family.
Inflammasomes − Caspase-1 Activation Scaffolds
T Cell Immune Checkpoints for Immuno-Oncology Research
AdipoGen Life Sciences offers a broad panel of immune checkpoint reagents, including recombinant proteins, antibodies and ELISA Kits.
Mesenchymal Stem Cells & CELLvo™ Matrix
Don’t Compromise Your Work Your work is important. Trust CELLvo™. The CELLvo™ Matrix is the only substrate available that closely mimics the full physical, structural, and biochemical microenvironment found in the human body. Together with our CELLvo™ Cells, cell culture
Inflammasomes and Gasdermin D Signaling Pathways
AdipoGen Life Sciences have a range of reagents for Gasdermin research
Autoimmune Disease Biomarkers APRIL & BAFF
The B cell-stimulating molecules, BAFF (B cell activating factor, also known as BLyS; TALL-1; CD257 or TNFSF13B) and APRIL (a proliferation-inducing ligand, also known as CD256 or TNFSF13), are critical factors in the maintenance of the B cell pool and
Antibody Validation
A committee, including Adipogen, made guidelines for antibody validation & detailed context-dependent measures to be followed by antibody suppliers.
3Helix Overview and Applications
Collagen is the most abundant protein in the human body. It is a critical component of almost all organs and tissues, providing the framework for cell attachment and growth. Collagen degradation regulates normal tissue remodelling which occurs during development, homeostasis
Revel the Mechanisms of Host Defense by Cross-regulation of Toll-like Receptor (TLR) Responses
A recent Nature Immunology paper describes the epigenetic landscape that results from the integration of the inflammatory cytokines type I interferons and TNF. This comprehensive epigenomics approach to the analysis of human macrophages showed that the proinflammatory cytokines TNF and type
Do You Really Know About Peptides?
Peptides are the organic molecule made up 2 to 40 amino acids, structurally same as protein but smaller. The bonds present in peptides are termed as a peptide bond (1). The bonds are formed between amino group (-NH2) of one amino acids and the
A Comprehensive Interpretation of Proteins
DEFINITION Proteins are the high molecular weight material which on complete hydrolysis gives amino acids. The word protein is derived from Greek word Proteiosmeans primary or holding first place or pre-eminent [1]. BIOMEDICAL IMPORTANCE OF PROTEIN They are: 1). Proteins are the main