ProSci offers reagents that can be used to study the actions of multiple immune checkpoint proteins such as CTLA-4, PD-1, & its ligands PD-L1 & PD-L2.
Immune Checkpoints
Viral Infectious Diseases
To support research & studies into infectious diseases, ProSci has reagents for the study of many viral disease agents inc. Covid, HIV, & Influenza.
Therapeutic Targets of the NAD+ Biosynthesis Pathway
CycLex NAMPT Colorimetric Assay Kit detects nicotinamide phosphoribosyltransferase (NAMPT) activity in recombinant NAMPT or endogenous NAMPT immunoprecipitated from cell extract.
Discover the Ab-Match ELISA Series: Unveiling Cancer Biomarkers and Beyond
The Ab-Match series by MBL are innovative ELISA kits for the detection of cancer antigens. These convenient kits come with all the necessary components for successful detection.
Tetramer Gating Strategy For True Positives Results
Investigators have developed a gating strategy that effectively minimises non-specific staining by incorporating a dump channel.
Histone deacetylase (HDAC): important consideration in regulating gene expression
Histone deacetylase (HDAC) plays a pivotal role in the regulation of gene expression through the modification of nucleosome structure.
The Impact of In Vivo Isotype Controls on Therapeutic Drug Development – MBL
The significance of antibody-based in vivo studies For both research and therapeutic purposes, antibodies can be used to affect cellular processes in vivo and are referred to as functional/in vivo grade antibodies. There is a wide range of applications for
SARS-CoV-2 (COVID-19) Mutations
As viruses create more of themselves, they mutate – single-point changes in genetic code. SARS-CoV-2 virus mutated to be more transmissible.
SARS-CoV-2 Open Reading Frames (ORFs)
The SARS-CoV-2 genome is ~29 kb divided into 10 ORFs. Each of these ORFs (except seemingly ORF10) is translated in 29 different proteins.
Immune Evasion of SARS-CoV-2
Research continues in understanding mechanisms of SARS-CoV-2 immune evasion. ProSci offers antibodies & recombinant proteins for SARS-CoV-2 research.