AdipoGen Life Sciences offers a broad range of unique and potent IL-33 research tools.
Interleukin-33 (IL-33) – A Potent Activator of Type 2 Immune Responses
GDF15, an Exercise-induced Factor regulating Appetite & Energy Expenditure
AdipoGen’s homodimeric protein Fc (LALA-PG)-KIH (human):GDF15 (mouse) (rec.) is a unique protein with long-acting high activity for in vivo studies.
Cellular Fibronectin (EDA) in Tumour Progression and Inflammation
AdipoGen is a manufacturer of the antibody clone IST-9, the standard antibody to detect and study cellular Fibronectin-EDA in IHC & ICC experiments.
InVivoKines™ – Proteins with Enhanced Activity & Stability for InVivo Research
InVivoKines™ are a range of recombinant fusion proteins for immunotherapeutic, preclinical & translational in vivo research, developed by AdipoGen.
Targeting GLP-1, GIP & GCG in Obesity and Type 2 Diabetes Research
Tirzepatide is a novel dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist.
New B7 Family Immune Checkpoint Proteins
Recently 5 new B7 family ligands, B7-H3, B7-H4, B7-H5, B7-H6 & B7-H7, were identified, all of them possibly of high interest in immunotherapy research.
HVEM – BTLA – LIGHT – CD160 Network
The checkpoint receptors/ligands system HVEM, LIGHT, CD160 and BTLA (CD272) is part of a complex network of overlapping receptor interactions.
OX40 – OX40L Pathway
OX40 is an activating receptor expressed on the surface of activated cytotoxic T cells & Tregs. OX40 activates & amplifies T cell responses.
TIGIT – CD155 – CD112 – CD226 Network
Tumour cells exploit the dominance of the inhibitory TIGIT pathway to avoid immune-mediated destruction.
LAG-3 – Major Histocompatibility Complex (MHC) – T Cell Receptor (TCR) Pathway
Dual inhibition of LAG-3 and other checkpoint pathways may synergistically increase T cell antitumour activity.