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Bioviotica

Bioviotica GmbH

The collaboration between Bioviotica GmbH and AdipoGen International allows us to bring the Bioviotica product range to our customers in the UK and Ireland.

The Source for Rare Active Natural Products

BioViotica Naturstoffe GmbH (BioViotica) was established in 2006 as a spin-off company from the University Göttingen, Germany and is dedicated to producing and characterizing “Rare Active Natural Products” as research reagents.

BioViotica focuses especially on the discovery and fermentation of rare biological active natural products from bacteria and fungus. The product portfolio of active natural products with a defined mode of action offered by BioViotica is of high interest to the academic, pharmaceutical high throughput and medicinal chemistry research covering biochemistry, molecular biology and pest management. The compounds are sold as single items or as Natural Product Libraries for screening purposes. BioViotica also offers services, including:

  • Structure determination of natural products from raw material.
  • Optimisation of microbial strains.
  • Custom strain cultivations.

BioViotica catalogue

New Biochemicals, Rare Natural Products & Antibiotics

AdipoGen manufactures a wide panel of new, innovative small molecule reagents, including Stem Cell Biology, Sonic Hedgehog, Protein Kinase, Cancer & Immunology and Obesity modulators. Search also through a broad panel of antibiotics and antimicrobial compounds for microbiota research. AdipoGen is also original manufacturer for many popular small molecule reagents and is exclusive provider of BioViotica natural products. "Get it from the Original Source"


Featured Products from BioViotica

Bafilomycin A1 (Macrolide antibiotic)

Specific vacuolar-type H+-ATPase inhibitor. Distinguishes among different types of ATPases. Inhibitor of endosomal acidification. Neuroprotective.

Concanamycin A (Antibiotic)

More potent and specific H+-ATPase inhibitor than bafilomycin A1. Inhibits acidification of organelles such as lysosomes and the Golgi apparatus. Blocks cell surface expression of viral glycoproteins without affecting their synthesis. Exhibits cytotoxic effects in a number of cell lines in a cell viability assay. Induces nitric oxide (NO) production. Inhibits autophagy.

Fumitremorgin C (Mycotoxin)

Tremorgenic. Potent and specific inhibitor of the breast cancer resistance protein (BCRP; ABCG2). Reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer agents in vitro.

17-DMAG

Less toxic, more potent synthetic derivative of geldanamycin. Inhibitor of angiogenesis. Inhibitor of heat shock protein 90 (HSP90). Inducer of apoptosis with higher antitumor activity than 17-AAG.

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