TIGIT Immune Checkpoint

Prosci logo, prosci incorporatedProSci Inc. offers an extensive range of antibodies and supporting tools to research TIGIT Immune Checkpoint. Read more about their range below, or click a link to jump to a specific section:

The T cell immunoreceptor with Ig and ITIM domains (TIGIT) is a member of the PVR (poliovirus receptor) family of immunoglobin proteins. Similar to other immune checkpoint proteins such as PD-1, TIGIT is upregulated on exhausted T cells in chronic viral infections and cancer. Blockade of both TIGIT and PD-1 pathways leads to tumor rejection in mice suggesting that it may be of therapeutic use against cancer.


 

Risk-Free™ Monoclonal TIGIT Products

ProSci’s Risk-Free™ antibodies are monoclonal antibodies made to improve in vivo studies. Unlike antibodies developed using proteins made in yeast or bacteria, Risk-Free™ antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein. Risk-Free™ means they are guaranteed to work for their approved applications.

Risk-Free™ Mouse Monoclonal TIGIT Set

ProSci’s Risk-Free™ Sets consists of several mAbs with different binding features allowing selection of the best clone.

Product SetSizeContentsDescription
Risk-Free TIGIT Set (PSI-RF16050)20ug / ClonePSI-RF16051, PSI-RF16054, PSI-RF16055, PSI-RF16056, PSI-RF16057, PSI-RF16058TIGIT antibodies were raised against the extracellular domain of human TIGIT.
Risk-Free™ Mouse Monoclonal TIGIT Antibodies

ProSci Risk-Free™ TIGIT products are rigorously tested and guaranteed to work for their designated applications.

Cat. No. ELISA WB ICC IF IHC Flow Conjugation
PSI-RF16051
+ - ++++ ++++ ++++ ++++ Available
PSI- RF16053 + - +++ +++ +++ ++++ Available
PSI-RF16054 ++++ +++ ++++ ++++ ++++ ++++ Available
PSI-RF16055 ++++ +++ ++++ ++++ ++++ ++++ Available
PSI-RF16056 ++++ ++++ ++++ ++++ ++++ ++++ Available
PSI-RF16058 ++ - +++ +++ +++ ++++ Available

 


Risk-Free™ Single Domain Monoclonal TIGIT Products

Llama single domain antibodies (sdAbs) offer unique characteristics amenable to many applications. These sdAbs demonstrate low nanomolar binding affinity and can be used for the various applications. Note: TIGIT single domain antibody should be stored in working aliquots at -20 °C, stable for up to one year. As with all antibodies, care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.


 

Related products

Antigens
Cat. No.Product TypeSpeciesTissue/CellDatasheet
PSI-RF16050-01Recombinant ProteinHumanHEK293 PDF
Lysates
Cat. No.Product TypeSpeciesTissue/CellDatasheet
PSI-RF10001-03Positive Control (Tissue Lysate)HumanSpleen PDF
PSI-RF10001-02Negative Control (Cell Lysate)HumanHEK293 PDF
Slides
Cat. No.Product TypeSpeciesTissue/CellDatasheet
PSI-RF10002-02Positive Control (Tissue)HumanSpleen PDF
PSI-RF10002-03Negative Control (Cells)HumanHEK293 PDF
Conjugates
Cat. No.HRPBiotinCustom
PSI-RF16051InquireContact Us
PSI-RF16053InquireContact Us
PSI-RF16054InquireContact Us
PSI-RF16055InquireContact Us
PSI-RF16056InquireContact Us
PSI-RF16058InquireContact Us

 

Additional TIGIT Antibody Products

Monoclonal antibodies are highly specific and recognize only one epitope on an antigen which generates consistent performance in quantitative detection applications regardless of production batch. Polyclonal antibodies have high affinity and recognize different epitopes on a specific antigen. Note: These antibodies can be stored at -20˚C and are stable for up to one year. Antibodies should not be exposed to prolonged high temperatures.

TIGIT Monoclonal Products
Cat. No.NameApplicationsDatasheet
PSI-77-084TIGIT Antibody [1G9] (PE)Flow PDF
PSI-77-086TIGIT Antibody [1G9] (APC)Flow PDF
TIGIT Polyclonal Products
Cat. No Antigen Range ELISA WB ICC IF IHC Flow Datasheet
PSI-61-342 12 - 142 0 ++++ 0 0 0 0 PDF
TIGIT Recombinant Protein Products
Cat. No.SequenceFusion TagSpeciesTissue/CellDatasheet
PSI-92-456Met 22 - Pro 141C-6 His TagHumanHuman PDF
PSI-92-550Gly 26 - Phe 135C-6 His TagMouseHuman PDF
PSI-96-722Met 22 - Pro 141C-Fc TagHumanHEK293 PDF

Additional TIGIT Information

ProSci products are distributed across Europe by Caltag Medsystems. If you have any questions about the products in this blog, please contact us.

TIGIT Immune Checkpoint
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